CJC-1295 + Ipamorelin
$39.00
CJC-1295 + Ipamorelin is a research blend of two growth hormone secretagogues that act on different receptors, supplied together in a single lyophilized vial.
CJC-1295 is a modified GRF(1-29) analog carrying amino acid substitutions that increase its resistance to enzymatic degradation; it binds the GHRH receptor on pituitary somatotroph cells. Ipamorelin is a selective agonist of the ghrelin receptor (GHS-R1a) and acts through a separate signaling pathway. The two are studied together to compare receptor-specific signaling against the combined preparation.
Researchers study this blend in:
- GHRH receptor and GHS-R1a binding assays
- Somatotroph cell culture models
- Receptor selectivity studies
- Comparative studies of single-agonist versus combined preparations
- Peptide stability and formulation research
For research use only. Not for human or veterinary use.
WHAT'S INSIDE
Two Peptides — How They Work Together
Each peptide targets a different step in the growth hormone release process:
| CJC-1295 (GHRH Analog) | Ipamorelin (GHRP) |
|---|---|
| A synthetic analog of growth hormone-releasing hormone (GHRH). It binds to GHRH receptors in the pituitary gland and signals it to produce more GH. Its extended half-life keeps this signal active for days providing a sustained elevation in GH and IGF-1 levels throughout the research protocol. | A selective growth hormone releasing peptide (GHRP). It triggers the release of GH already stored in the pituitary, creating a clean, sharp GH pulse. Unlike older GHRPs, Ipamorelin does not raise cortisol, prolactin, or cause significant hunger making it the most selective and well-tolerated GHRP studied to date. |
The combination produces 2-3x more GH than either peptide alone. CJC-1295 sustains the baseline elevation. Ipamorelin adds the pulse. Together they replicate the natural rhythm of youthful GH secretion more closely than any single compound can achieve.
MECHANISM
How Does It Work?
By restoring growth hormone levels through the body’s own pituitary pathway, the CJC-1295 + Ipamorelin blend activates several downstream research effects:
| Fat Metabolism | Muscle Preservation & Recovery |
|---|---|
| Elevated GH increases lipolysis the breakdown of stored fat for energy. Research models show improvements in body composition, particularly reductions in visceral and subcutaneous fat over time. | GH and IGF-1 support protein synthesis and lean tissue preservation. Research models show faster recovery from muscle stress and improved nitrogen retention during protocols. |
| Sleep Quality | IGF-1 Elevation |
|---|---|
| GH is naturally released during deep sleep. The CJC-1295 + Ipamorelin blend amplifies slow-wave sleep GH pulses, with research subjects reporting improvements in sleep depth and recovery quality. | By stimulating GH production, the blend also raises IGF-1 the downstream anabolic hormone responsible for tissue repair, cellular growth, and metabolic regulation. |
| Anti-Aging Metabolic Effects | No Cortisol or Prolactin Spike |
|---|---|
| GH declines significantly with age. Restoring GH levels through pituitary stimulation is one of the most studied approaches to age-related metabolic decline making this blend a central tool in longevity research protocols. | Unlike older GH secretagogues (GHRP-2, GHRP-6), Ipamorelin does not stimulate cortisol or prolactin release. This makes the blend significantly cleaner in research models fewer unwanted hormonal effects. |
The reason this combination dominates GH research protocols: it works with the body’s own feedback system. The pituitary still self-regulates avoiding the suppression and dependency risks associated with exogenous synthetic HGH administration.
DISCLAIMER
This product is exclusively for laboratory research. Not approved for human or veterinary use. All products sold by Ikon Peptides are intended exclusively for in-vitro laboratory research. Not approved for human consumption or veterinary use. These statements have not been evaluated by the FDA.
PHYSICAL PROPERTIES
Key specifications for handling and storage in laboratory settings:
| Composition | CJC-1295 (no DAC) + Ipamorelin blend |
| CJC-1295 MW | 3,367.9 g/mol — 29 amino acids (Mod GRF 1-29) |
| Ipamorelin MW | 711.9 g/mol — 5 amino acids |
| Form | White lyophilized powder blend |
| Solubility | Water-soluble |
| Purity | 98%+ (HPLC verified — each component) |
| Administration | Subcutaneous injection |
| Storage | Refrigerated 36-46 F (2-8 C). Protect from light. Avoid freeze-thaw cycles. |
| Stability | 24 months lyophilized. Use within 30 days once reconstituted. |
POTENTIAL SIDE EFFECTS IN RESEARCH
CJC-1295 + Ipamorelin is considered one of the cleanest GH-stimulating blends in current research with a significantly milder side effect profile than synthetic HGH or older GH secretagogues. Researchers should monitor and document all observations.
| Injection Site Irritation | Mild Headache |
|---|---|
| Mild redness or discomfort at the injection site. The most commonly reported observation. Typical of peptide administration and resolves quickly. | Occasionally reported in the first few doses of a protocol. Generally brief and resolves on its own. More common at higher concentrations. |
| Water Retention | Mild Fatigue or Drowsiness |
|---|---|
| Mild fluid retention has been noted in some research subjects — consistent with GH elevation. Generally mild and less pronounced than with synthetic HGH. | Some subjects report temporary drowsiness following administration — particularly when dosed at night. Consistent with GH’s role in promoting slow-wave sleep. |
| Mild Nausea | Lightheadedness |
|---|---|
| Rarely observed. Unlike older GHRPs, Ipamorelin does not cause significant hunger or GI distress. Nausea is mild and transient when reported. | Occasional mild dizziness noted in some subjects, particularly early in a protocol. Attributed to GH-induced shifts in insulin sensitivity. Short-lived. |
No cortisol spikes, no prolactin elevation, no extreme hunger the hallmarks of older GH secretagogues are not observed with this blend at standard research concentrations. It is consistently described as the cleanest GH-stimulating protocol in current research.
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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