Semax 10MG
$35.00
Semax is a synthetic peptide consisting of the ACTH(4-7) fragment extended with a Pro-Gly-Pro sequence, which increases its resistance to enzymatic degradation. It does not retain the corticotropic activity of the full ACTH molecule.
Published research characterizes it as a modulator of BDNF and NGF expression and of the associated TrkB receptor signaling, with reported effects on monoamine turnover in animal-model brain tissue.
Researchers study Semax in:
- BDNF and NGF expression assays
- TrkB receptor signaling studies
- Neuronal cell culture models
- ACTH fragment structure-activity studies
- Peptide stability research
For research use only. Not for human or veterinary use.
MECHANISM
How Does It Work?
Semax works through four distinct pathways in the brain, each one studied independently and together as part of a broader neuroprotective effect:
| BDNF Upregulation | Dopamine & Serotonin Modulation |
|---|---|
| Semax increases production of BDNF the protein that tells the brain to grow new neurons, strengthen existing connections, and improve learning and memory. Think of BDNF as fertilizer for the brain. | Semax influences the dopamine and serotonin systems the pathways responsible for motivation, mood, and focus. Researchers observe improvements in attention and emotional balance in study models. |
| Neuroprotection | Anti-Inflammatory Effect on the Brain |
|---|---|
| In stroke and brain injury research models, Semax has shown the ability to reduce neuron death and support recovery. It activates protective genes and reduces the damage caused by reduced blood flow to the brain. | Semax suppresses inflammatory gene expression in the brain. Neuroinflammation is linked to cognitive decline, brain fog, and neurodegenerative conditions making this one of the most studied aspects of the compound. |
What sets Semax apart from other nootropic research compounds is its delivery. It is typically administered intranasally which allows it to partially bypass the blood-brain barrier through olfactory pathways and reach the central nervous system faster and more efficiently than most compounds.
PHYSICAL PROPERTIES
Key specifications for handling and storage in laboratory settings:
| Peptide Structure | Synthetic heptapeptide — ACTH(4-7)PGP fragment |
| Molecular Weight | 887.0 g/mol |
| Form | White lyophilized powder |
| Solubility | Water-soluble |
| Purity | 98%+ (HPLC verified) |
| Administration | Intranasal (most common in research) or subcutaneous injection |
| Storage | Refrigerated 36-46 F (2-8 C). Protect from light. |
| Stability | 24 months lyophilized. Use within 30 days once reconstituted. |
POTENTIAL SIDE EFFECTS IN RESEARCH
Potential Side Effects in Research
Semax has a well-established safety profile across decades of research. Side effects are generally mild, infrequent, and dose-dependent. Researchers should monitor and document all observations.
| Nasal Irritation | Mild Headache |
|---|---|
| The most commonly reported observation with intranasal administration. Temporary irritation or dryness in the nasal passage. Typically short-lived. | Occasionally reported at higher doses in some subjects. Generally resolves on its own without intervention. |
| Fatigue or Lightheadedness | Increased Anxiety (Rare) |
|---|---|
| Mild fatigue noted in some research subjects, particularly early in a protocol. Usually transient and dose-dependent. | In rare cases, heightened alertness has tipped into mild anxiety in some models. More common at elevated doses. |
| Altered Mood or Irritability | Appetite Changes |
|---|---|
| Due to its effects on dopamine and serotonin pathways, subtle mood shifts have been observed in some subjects during research protocols. | Minor changes in appetite have been noted in some study models. Effect is mild and not considered dose-limiting in research settings. |
Semax has been used in clinical settings in Russia for decades with no serious adverse effects documented at standard research concentrations. It is considered one of the safest neuropeptides currently under investigation.
DISCLAIMER
This product is exclusively for laboratory research. Not approved for human or veterinary use.
All products sold by Ikon Peptides are intended exclusively for in-vitro laboratory research. Not approved for human consumption or veterinary use. These statements have not been evaluated by the FDA.
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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